Wednesday, April 30, 2008

Delysid

Albert Hofmann, father of the mind-altering drug LSD whose medical discovery grew into a notorious "problem child," died Tuesday. He was 102.

Hofmann's hallucinogen inspired millions in the 1960's hippie generation. For decades after LSD was banned in the late 1960s, Hofmann defended his invention.

The Swiss chemist discovered lysergic acid diethylamide-25 in 1938 while studying the medicinal uses of a fungus found on wheat and other grains at the Sandoz pharmaceuticals firm in Basel.

He became the first human guinea pig of the drug when a tiny amount of the substance seeped onto his finger during a repeat of the laboratory experiment April 16, 1943.

"I had to leave work for home because I was suddenly hit by a sudden feeling of unease and mild dizziness," he wrote in a memo to company bosses. "Everything I saw was distorted as in a warped mirror," he said, describing his bicycle ride home. "I had the impression I was rooted to the spot. But my assistant told me we were actually going very fast."

For a time, Sandoz sold LSD 25 under the name Delysid, encouraging doctors to try it themselves. It was one of the strongest drugs in medicine, with just one gram enough to drug an estimated 10,000 to 20,000 people for 12 hours.

"LSD can help open your eyes," he once said. "But there are other ways: meditation, dance, music, fasting."

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